Description
MTHFR Mutation is a disease of the MTHFR Gene.
The Genetic disorder that disrupts the normal functions of the body is MTHFR Mutations.
The MTHFR gene produces the MTHHR enzyme.
MTHHR enzyme works with vitamin B9 in breaking 5, 10 Methylenetetrahydrofolate to 5 Methyltetrahydrofolate. 5 Methyltetrahydrofolate aids the conversion of Homocysteine amino acid into an essential amino acid called Methionine.
The MTHFR gene is responsible for making Methionine. Methionine has various functions.
Methionine functions are
It is converted into SAM-e ( s-adenosylmethionine ). SAM-e is responsible for Cell growth, repair and maintenance. It is responsible for production and breakdown of brain chemicals like Serotonin, Dopamine and Melatonin. It supports anti inflammatory and immune functions of the body.
Diseased State
Any problem with the MTHFR gene produces defective MTHFR enzyme. The produced enzyme does not work correctly and leads to following.
Body is unable to breakdown toxins or heavy metals. Excess buildup of iron, lead, mercury or copper in the body. Glutathione production decreases. MTHFR enzyme is not able to breakdown folate vitamins. The levels of Homocysteine rises in the body. This increases the risk of
Anemia
Stroke
Stress
Migraine
Depression
Miscarriage
Breast Cancer
Heart diseases
Blood pressure
Dementia rises
Prostate Cancer
Arteriosclerosis
Venous Thrombosis
Irritable Bowel Syndrome
Fatty Liver Degenerative Disease
Arteriosclerotic Vascular Diseases
Types of MTHFR Mutation
Homozygous : When both the parents pass on the same gene to the child it is called Homozygous. The gene may be 677 or 1298.
Heterozygous : When one parent passes on 677 or 1298 and the other parent passes a normal gene.
Compound Heterozygous : When one parent passes 677 gene and the other parent passes the 1298 gene.
If not treated properly, MTHFR Mutation may cause
Alzheimer
Spina Bifida
Schizophrenia
Bipolar Disorder
Vascular Dementia
Parkinson’s Disease